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In the murine model of colon cancer (CT26), it enhanced the anti-tumor immune response, inhibited tumor growth, promoted dendritic cell maturation, and activated natural killer cells and CD8 + T cells
These pretreatment effects on acquisition of cocaine self-administration were no longer present following acute blockade of 5-HT 1A receptors with WAY-100,635 ( Figure 4B ) or acute blockade of D 2 receptors with L-741,626 ( Figure 4C )
It is known that tobacco smoke can interact with drugs both through pharmacokinetic and pharmacodynamic mechanisms [24]
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