Sequencing results of homozygous mice confirmed the successful insertion of both LoxP sites (Fig
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The stratification into mechanistic subtypes, such as neuroinflammation-dominant, could be guided by biomarkers like specific cytokines (e.g., associations found between interleukin-6 and tinnitus intensity (Tanaka et al., 2024)) or by functional imaging with specific tracers
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Haptoglobin levels are very low in newborns, but there are measurable levels by about 3 months of age, and these increase gradually throughout childhood ( 125 )