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Males were also initially excluded since there were concerns about the potential for testicular toxicity at the outset of the trial that emanated from the aforementioned toxicology study in Sprague Dawley rats (see Supplementary Results for complete details of this preclinical study)

Carry a digital thermometer to check medication temperature after each transit period

OTC Anti-Nausea Medications When symptoms spike, over-the-counter anti-nausea or antacid medications can provide short-term relief

Here is the simple version