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PLoS ONE 9:e100980

Preventive cycling: exploring whether periodic supportive consultations may benefit certain individuals

The 500 mcg per-capsule dose mirrors the per-day intake used in the bulk of rodent oral studies, and the gastric origin of the parent molecule provides a biological rationale for stability through the GI tract a feature documented across multiple oral-administration preclinical models

TB-500 has also been studied for anti-inflammatory properties and angiogenic effects