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Domain of Applicability Empirical domain of applicability Sex : The AOP is applicable to males and females

The medication carries a risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Mogos R, Gheorghe L, Carauleanu A, Vasilache IA, Munteanu IV, Mogos S, Solomon-Condriuc I, Baean LM, Socolov D, Adam AM, Preda C (2024) Predicting unfavorable pregnancy outcomes in polycystic ovary syndrome (PCOS) patients using machine learning algorithms

Seem little drowsy after the initial injection

A 2017 study showed 12% faster nail growth and 42% reduction in broken nails after 24 weeks (Hexsel et al