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1 Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University of Jerusalem, Jerusalem, 2 Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of M, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, 3 Hadassah Medical Center, Department of Endocrinology, Hebrew University of Jerusalem, Jerusalem, Israel

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Importantly, inhibition of FOXOs in such cells tipped the balance from senescence towards apoptosis