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14.2 Bardet-Biedl Syndrome (Adults and Pediatric Patients Aged 6 Years and Older) Clinical Trial Overview The efficacy of IMCIVREE for weight reduction in adults and pediatric patients aged 6 years and older with obesity and a clinical diagnosis of Bardet-Biedl syndrome (BBS) were assessed in a 66-week clinical trial, which included a 14 week randomized, double-blind, placebo-controlled period and a 52-week open-label period (Trial 2 [ NCT03746522])

While described as nonselective at other melanocortin receptors, its clinical effects are predominantly MC1R-mediated

Reconstitution transforms a freeze dried peptide into a liquid solution that can be measured accurately

Access to GLP-1 was possible through insurance, though Cohen acknowledged many people still struggle with availability

Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes