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In addition to these direct anticancer mechanisms, lignans such as schisandrin B and gomisin A have been shown to reverse MDR by inhibiting P-gp, a drug efflux transporter associated with reduced chemotherapy efficacy [90, 91]

Instrument parameters: excitation wavelength was 485 nm, emission wavelength was 515 nm

INTRODUCTION Vitamin B12 is essential for DNA synthesis, red blood cell formation, and neurologic function[] and is also involved in the metabolism of fat and carbohydrate.[] The clinical manifestations of vitamin B12 deficiency are the effects of depletion on multiple systems, and their severity varies greatly