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Men with a personal or strong family history of medullary thyroid cancer should avoid GLP-1 agonists due to animal study signals, though human data remain reassuring

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There is one example of peptide extended release which is Bydureon or exenatide (39 amino acids, half-life of 2.4hrs) developed for T2D

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BPC-157, perhaps owing to its gastric origins, demonstrates unusual resistance to these harsh conditions