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Dulaglutide was less studied but showed promising signs in animals, increasing beneficial bacteria like Bacteroides, Akkermansia, and Ruminococcus

Rare but serious (seek medical attention): Significant swelling of face, hands, feet

doi: 10.3389/fimmu.2024.1485523 19 MaiorinoMConradMUrsiniF

Potential translation of the mechanism presented by Yun et al

ADA Standards of Care 2025) recommend that patients with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD) (or high risk) should be on a GLP-1 RA with proven CV benefit (or an SGLT2 inhibitor) as part of their regimen, independent of A1c, because of the outcome benefits ( [9] ) ( [144] )