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The Metabolomic Effects of Tripeptide Gut Hormone Infusion Compared to Roux-en-Y Gastric Bypass and Caloric Restriction

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In more severe cases, individuals might experience difficulty breathing, which warrants immediate medical attention

The potential mechanisms underlying the increased risk of gastric aspiration are not fully understood, and nowadays it is explained mainly by delayed gastric emptying and inhibition of gastrointestinal motor function that GLP-1-RAs exert through both central motor nuclei and vagal afferents [13, 14]

What happens when a side effect is bothersome but not dangerousthat is, a drug is causing some type of discomfort, but the benefits are so substantial that the unpleasant side effects have to be mitigated or tolerated in service of a greater goal