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Prospective, double-blind, randomized, placebo-controlled comparison of acetazolamide versus ibuprofen for prophylaxis against high altitude headache: the Headache Evaluation at Altitude Trial (HEAT)

Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia

In one clinical trial assessing the efficacy of phentermine and vitamin B-12 for weight loss, vitamin B-12 injections were used as the sole ingredient of 1,000 mg per week

The general principle of escalation observed in the trial involved starting at a low dose and titrating upward at approximately four-weekly intervals, with the highest-dose arm targeting 12 mg once weekly

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