Based on the reviewed studies, the average weight loss achieved with these pharmacological agents is approximately 15% for semaglutide, 8.4% for liraglutide, 8-10% for phentermine, and 5-10% for orlistat
Tier 2 (preferred brand) has moderate copay
Exercise, physical activity, and GLP-1 dry mouth Physical activity creates additional challenges for GLP-1 users dealing with dry mouth
Baseline laboratory investigations may include lipid panel, hemoglobin A1c, and liver function tests , depending on the patient's comorbidity profile
If multiple competitors enter quickly, Canadian list prices for semaglutide could reset materially, improving access for type 2 diabetes and obesity while easing pressure on public and private plans