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Coulter also cautions patients against stopping the medication abruptly

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"We started by thinking maybe the immune system is involved," says Harvard stem cell scientist Ya-Chieh Hsu

The phase 3 TRIUMPH-4 trial confirmed these findings

Within three to four years, the oral small-molecule sub-class is likely to have at least one or two more approved members, and price competition will start to put pressure on the injectables in cash-pay and lower-income markets