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Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury

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Figure: Cleaving Disulfide Bonds in Proteins Cysteine Redox Chemistry The sulfur in cysteine is redox-active and hence can exist in a wide variety of states, depending on the local redox environment and the presence of oxidzing and reducing agents

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Wang L, Cai H, Hu Y, Liu F, Huang S, Zhou Y