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doi:10.1016/j.freeradbiomed.2005.08.045

Paget observed that primary tumor cells of a given type of cancer preferentially metastasized to one or more particular distant organ sites, detectable metastases only developed at those sites (soils) where the tumor cells (seeds) were adapted for survival and proliferation [21]

Neuron 97 , 434449.e4 (2018)

The melanocortin 5 receptor (MC5R) appears to be distributed across multiple tissues, although what role it might serve remains unclear

238 However, Wnt binding FZD receptors and the redundant coreceptors low-density lipoprotein receptor-related proteins (LRP)5/6 together activate dishevelled (DVL)