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2p) and a higher percentage of rats with a recognition score 60 Hz) may also be related to increased bursting rates of sub-cortical DA-VTA neurons [97], consistent with our previous evidence showing that adolescent THC treatment leads to persistent hyperactivation and increased bursting rates of DA cells [4, 5, 10]

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In fact, the opposite is usually true

Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia

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