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This is the same physiologic process seen when someone stops lifting weights: muscle size decreases because the stimulus is gonenot because muscle is being destroyed. Common Misconception: GLP-1 Drugs Burn Muscle Reality: Muscle loss during GLP-1associated weight loss is driven by reduced mechanical load and insufficient protein/calories , not by a toxic or catabolic drug effect. When Lean-Mass Loss Becomes True Muscle Wasting True muscle wasting is uncommon with GLP-1 therapy and is usually related to undernutrition , not the medication itself

Not necessarily bad, not catastrophic like some internet horror stories suggest, but definitely weird

When pharmaceutical ingredient supplies tighten, prices increase

Insulin, for example, is a peptide, as are widely used GLP-1 medications for diabetes and obesity such as Ozempic and Wegovy

All three medications are only available with a prescription, and there are no approved generic versions, the FDA said in May