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Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein

10.1074/jbc.M116.773176 J Biol Chem

[DOI] [PMC free article] [PubMed] [Google Scholar] 154.Kirisattayakul W., Wattanathorn J., Tong-Un T., Muchimapura S., Wannanon P., Jittiwat J

Translational success will require (i) rigorous preclinical-to-clinical pipelines that include long-term toxicity and biodistribution studies, (ii) GMP- compliant manufacturing to ensure reproducibility and scalability, (iii) adaptive trial designs capable of evaluating patient-specific nanotherapies, and (iv) clearer regulatory alignment across FDA/EMA to classify and approve multifunctional nanoplatforms

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