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The limited absorption of the nasal cavity restricts the amount of drug being effectively absorbed, making class I drugs (high permeability, high solubility), according to the Biopharmaceutics Drug Disposition Classification System (BDDCS), particularly suitable for nasal delivery (Ugwoke et al., 2001)

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Oral green tea preparations, by contrast, have been reviewed by Cochrane and found to produce only a small, statistically non-significant weight change