breast cancer and glp-1 Study links drugs to lower diagnosis rates GLP-1s: Weight Loss and Survival

Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

doi: 10.2337/diabetes.48.5.1026 88 ThorkildsenCNeveSLarsenBDMeierEPetersenJS

In the clinical setting, a study comparing lipid profiles of patients treated with glipizide or metformin found significant increases in both groups in phosphatidylcholine (PC) lipids and decreases in SM species

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Our findings raise the question of whether ATF4-mediated ISR is generally present in these TKI-insensitive CML cells and what causes the activation of ATF4 translation in these cells