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We observed a consistent increase in sensitivity, or reduced IC 50 value, for mutant cells treated with doxycycline but not parental OVCAR5 cells, indicating that induction of mutant p53 sensitized cells to APR-246 (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Huang S., He T., Yang S., Sheng H., Tang X., Bao F., Wang Y., Lin X., Yu W., Cheng F., et al

Owing to these, researchers began to search for the relationship between autism and nDNA mutations