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EMAs safety committee, the PRAC, has started a review of medicines containing semaglutide following concerns regarding an increased risk of a non-artheritic anterior ischemic optic neuropathy (NAION), a rare eye condition, as suggested in two recent observational studies, while two other recent observational studies do not suggest an increased risk, the EMA stated

Nonarteritic anterior ischemic optic neuropathy (NAION) is another ocular disease that often presents with a sudden onset of painless monocular visual loss with altitudinal visual field defects