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Ferroptosis affects the proliferation and apoptosis of granulosa cells (GCs), affecting endocrine and metabolic processes ( Figure 4 )
SUPPLEMENTARY TABLE Demographics of Participants in Phase 3 Trials Supported by NIH Centers and Institutes * Data on Asian enrollment in 2013 and 2014 were affected by large Asian representation in trials run by the National Institute of Child Health and Human Development (for which enrollment data are not available for 20162018)
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It does not appear to interact negatively with other medications and has been well-tolerated across a wide range of doses in animal models
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