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Early eat-me signals described in the literature are immature sugar structures that lack sialic acid, and the asialoglycoprotein receptor was found to be responsible for the targeted deposition of apoptotic hepatocytes [215]

These alterations were accompanied by increased expression of Cas-3 and NF-B, elevated levels of pro-inflammatory cytokines (TNF-, IL-6), and significant oxidative stress, as evidenced by increased MDA and decreased antioxidant enzyme levels (SOD, CAT, GSH-Px)

According to a study by Ottaviani et al ., peroxidated squalene induces the inflammatory mediators, which may play a role in pathogenesis of acne vulgaris

Cluster analysis showed that 31.7% of the Long COVID patients had severe abnormalities in SpO2, body temperature, increased oxidative toxicity (OSTOX) and lowered antioxidant defenses (ANTIOX), and increased total Hamilton Depression (HAMD) and Anxiety (HAMA) and Fibromylagia-Fatigue (FF) scores

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