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Effective transdermal drug delivery generally requires appropriate lipophilicity and molecular propertiesberberine's physicochemical characteristics are suboptimal for this route, primarily due to its ionic charge and poor lipid solubility

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Sorli C, Harashima SI, Tsoukas GM, et al

Lysozymes Lysozymes are glycoside hydrolases that cleave -(1,4)-glycosidic bonds of bacterial cell walls [44]

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