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22 ), an ancestrally resurrected sequence from Basidiomycete PM1 fungi, which may offer improved heterologous expression and activity because of the generalist nature of ancient enzymes 27

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In the case of GLP-1 medications, they obtain semaglutide or tirzepatide active pharmaceutical ingredients (APIs) and formulate them into injectable solutions or oral tablets

The cohorts spanned lung, colon, kidney, bladder and skin cancer, covering diverse treatment strategies, such as ICI with or without FMT, chemotherapy (CT), radiotherapy (RX) and/or tyrosine kinase inhibitors (TKIs) (Supplementary Table 1ak)