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Lenti MV, Rugge M, Lahner E et al (2020) Autoimmune gastritis

With so many benefits, its clear why B12 is a popular supplement choice

A subsequent addition of 0.004% digitonin made cells (approximately 2.106 cells) permeable to small molecules including respiratory substrates, with the subsequent dilution of respiratory substrates and progressive arrest of oxygen consumption

This barrier, called the intestinal epithelial barrier, is crucial for maintaining a healthy gut and preventing conditions like leaky gut syndrome (intestinal permeability)