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In this multicenter study conducted across 22 countries, participants (67.6% females and 72% White) received once-weekly subcutaneous administration of CagriSema ( n = 2,108) with dose escalation from 0.25 mg to a maximum of 2.4 mg for each drug, in addition to lifestyle intervention, compared with placebo ( n = 705)

Published 2018 Jul 7

We next examined whether these metabolic and viability phenotypes reflected defects in pre-mRNA splicing (Fig

A., Gardner, D