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Research demonstrates that estrogen deficiency-induced bone loss due to estrogen shortage significantly differs among mouse strains, suggesting that genetic factors regulate PMO bone loss via various pathways ( Genetic background influences bone loss in PMO by affecting the GM, establishing baseline bone mass, regulating the distribution of antigen-presenting cells (APCs), and influencing the development and activity of the host immune system

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The Indian skin is prone to hyperpigmentation, especially in areas that chronically rub against each other or if there is any undue friction

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