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Kengen SW, Bikker FJ, Hagen WR, de Vos WM, van der Oost J

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These studies generally demonstrate favorable safety profiles, although their therapeutic efficacy is often limited by poor aqueous solubility, rapid metabolism, and low systemic bioavailability

Alternative medications like DPP-4 inhibitors, GLP-1 receptor agonists, SGLT2 inhibitors, sulfonylureas, and TZDs are available for managing blood sugar levels, but the suitability of these options should be determined by a healthcare professional

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