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2.2.2 Key driving factors 2.2.2.1 Iron overaccumulation The core driving factor of ferroptosis is the excessive accumulation of iron, and this process is mainly regulated by iron homeostasis regulators such as transferrin receptor (TFR), ferritin, and ferroportin (FPN) (Zhang et al., 2025c)
Industry forecasts project the market to exceed $100 billion by 2029, driven by expanded therapeutic indications and the anticipated launch of oral formulations
Better sleep further amplifies recovery and muscle protein synthesis, creating a compounding benefit
Measurement of plasma Triglycerides (TG) The plasma triglyceride (TG) levels of both patients and healthy controls were quantified by enzymatic colourimetric assay using Randox Triglycerides assay kit (Randox Laboratories Ltd., Crumlin, UK)