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This review explores the molecular mechanisms of ferroptosis and its involvement in CKD development, providing novel insights for the prevention and treatment of CKD

A non-significant difference in the brains GSH and T-SOD levels was recorded between the AST-supplemented and control groups

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This process is self-reinforcing: inflammation-derived oxidative stress promotes further ferroptosis, while dying ferroptotic cells release DAMPs that activate surrounding structural and immune cells, intensifying the inflammatory response ( 6.2 Classical and non-classical pathways of ferroptosis regulation The regulation of ferroptosis in the asthmatic airway involves both canonical and alternative mechanisms that determine cellular susceptibility to this form of cell death

absorbance at 450nm in a microplate reader