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The severity of the vitamin B12 deficiency Presence of underlying health conditions Patients response to initial treatment Age and weight considerations Healthcare providers can adjust the vitamin B12 injection dosage based on these factors

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The mechanism works regardless of starting body fat level, though individuals with BMIs above 40 may benefit from the full 12mg dose more than those in the 30-35 BMI range

There are dozens of contributing causes for why someone may gain weight including sleep disturbances, hormonal changes, inflammation, stress, microbiome alterations, social determinants of health, emotional coping strategies, etc

The FDA recently ordered producers to wind down the compounding of these drugs on the grounds that there were no longer the shortages of the originator drugs that had justified temporary concessions to ensure patients had access to the medications