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L-carnitine attenuates cardiac dysfunction by ischemic insults through Akt signaling pathway

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The calcium-dependent binding of CAO to ANT induces a conformational change (Halestrap et al., 2002) which results in the opening of the mitochondrial permeability transition pore (MPTP) and allows the equilibration of small solutes and the release of pro-apoptotic proteins from the intermembrane space

This innovative approach could potentially improve patient compliance and outcomes compared to injectable therapies

Abdominal pain and depression, not bowel habits, predict health care utilization in patients with functional bowel disorders