Miyaji T, Kuromori T, Takeuchi Y, Yamaji N, Yokosho K, Shimazawa A, Sugimoto E, Omote H, Ma JF, Shinozaki K
We prioritize bioavailability because we want our community to feel the results of their investment
A folate-dependent enzyme, requiring vitamin B12, is needed to synthesize DNA
Plateaus Are Normal: What to Expect: Initial rapid loss (first 3 months) Continued steady loss (months 4-12) Plateau period (months 13-18) Final adjustments (months 19-24) Plateaus dont mean failure: Natural part of weight loss Body adjusting to new weight May need dose optimization Continue medication to maintain loss Non-Scale Victories: Results Beyond the Number: Even if weight loss is slower than hoped, patients experience: Reduced waist circumference: Lost inches even when scale stalls Better blood pressure: 5-10 mmHg reduction common Improved blood sugar: A1C reductions of 1-2 points Better cholesterol: 10-20% improvement in lipids Increased energy: From weight loss and metabolic improvements Improved mobility: Easier movement, less joint pain Better sleep: Improvement in sleep apnea Enhanced quality of life: Confidence, mood, relationships These improvements matter regardless of exact pounds lost

GLP-1s can also restore fertility in some women who previously had irregular ovulation, so reliable contraception matters if pregnancy is not planned