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In diet-induced obese mouse models, chronic dosing produced dose-dependent reductions in food intake, body weight, and adipose mass, alongside improved glucose tolerance during oral glucose challenges

DOI: 10.1016/j.matbio.2015.01.004 [Google Scholar] Caligiuri A, Gentilini A, Pastore M, Gitto S, Marra F

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Chronic riluzole treatment increases glucose metabolism in rat prefrontal cortex and hippocampus