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Sociodemographic characteristics Diagnosis (vitamin B12 deficiency or pernicious anaemia), age, sex, education level, employment status, country of residence (England, Wales, Scotland, Northern Ireland, Republic of Ireland), region of residence (nine English regions, according to the Office for National Statistics, Wales, Scotland, and Northern Ireland) were assessed using the questions in Supplementary Table S1

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Digestive symptoms are already the most common side effects associated with GLP-1-based medications, so combining two drugs with similar actions could intensify these effects