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However, we identified a single nucleotide polymorphism (SNP) (Suppl

Although nicotinamide adenine dinucleotide (NAD+), a critical redox cofactor, declines in post-ovulatory oocytes, NR supplementation effectively prevents this loss, restoring metaphase II (MII) oocyte quality by maintaining chromosomal integrity and alleviating mitochondrial dysfunction, which may enhance ART success ( In addition to these supplements, salidroside has been found to reduce ROS levels and enhance intracellular glutathione (GSH) concentrations, promoting cytoplasmic maturation via increased ATP production, mitochondrial membrane potential, and mtDNA copy number

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[DOI] [PMC free article] [PubMed] [Google Scholar] 231.van der Louw EJ, Williams TJ, Henry-Barron BJ, et al

doi: 10.1146/annurev-med-062613-093128 31 WangYAnHLiuTQinCSesakiHGuoSet al