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10.1016/j.amjmed.2017.03.010 52 LebrunL
Its part of a class of drugs called glucagon-like peptide 1 (GLP-1) receptor agonists, which help people with Type 2 diabetes lower their blood sugar and reduce their risk for cardiovascular disease
The intestinal flora syn-thesizes SCFAs, such as butyric, acetic, and propionic acids, by fermenting undigested dietary fiber (Li et al., 2022)
Interestingly, MTX + mildronate samples (group 5) showed more severe tubular damage and degenerative changes (red arrow) accompanied with hyperplasia of mesangial cells of renal corpuscles (black arrow head), mild interstitial inflammatory cells infiltrates were showed (red arrow head) with obvious higher fibroblastic activity as well as periglomerular and interstitial fibrosis (dashed arrow)
