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ABSTRACT Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have demonstrated considerable efficacy in the treatment of diabetes and obesity, it is essential to recognize that their use is associated with certain intrinsic risks that must not be disregarded

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If the vial has been at room temperature for more than a day or two, use it within the 21-day room temperature window rather than refrigerating it again

It requires a valid prescription from a licensed medical professional

This typically means the first 4 to 8 weeks of treatment, with symptoms peaking around weeks 2 to 4