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Typically, CAFs overexpress alpha-smooth muscle actin (-SMA), Vimentin, platelet-derived growth factor receptor (PDGFR), PDGFR, Tenascin-C, Caveolin 1, fibroblast activation protein (FAP), and ferroptosis suppressor protein 1 (FSP1) [66]
Research by Goldstein and colleagues, published in Annals of the New York Academy of Sciences, characterized Thymosin Beta-4's role in promoting cell migration, reducing inflammation, and accelerating tissue remodeling after injury
Thus, peptides became an invaluable tool in both research and medical applications
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