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Shortened telomeres are associated with cellular aging, and compounds that influence this pathway are of growing interest in longevity medicine

The AAP guideline recommends IHBLT as first-line therapy for all children with overweight or obesity, defined as at least 26 contact hours over 3 to 12 months of family-based, multicomponent behavioral treatment [7]

The REWIND trial with dulaglutide included many patients without established ASCVD and demonstrated a consistent reduction in MACE, supporting a role in primary prevention, although the effect size was modest

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These are often less expensive than brand names but are not FDA-approved