Clinical evidence: in a cohort study involving 4,125 elderly individuals, higher cereal-derived RS intake (15 g/day) was associated with a 28% reduction in serum IL-6 levels and a 35% reduction in TNF- levels compared to low-RS intake ( 90%sufficient to meet 25% of daily protein requirements and support tryptophan (serotonin precursor) and tyrosine (dopamine precursor) supply (304)
J Exp Med 182:178592, PMID: 7500023 Neuschwander-Tetri BA, Bellezzo JM, Britton RS, Bacon BR, Fox ES (1996) Thiol regulation of endotoxin-induced release of tumor necrosis factor a from isolated rat Kupffer cells
Further scientific studies are imperative to elucidate its therapeutic potential and underlying molecular pathways (Oyeleke and Owoyele, 2022)
Varga D, Hoegel J, Maier C, Jainta S, Hoehne M, Patino-Garcia B, Michel I, Schwarz-Boeger U, Kiechle M, Kreienberg R, Vogel W: On the difference of micronucleus frequencies in peripheral blood lymphocytes between breast cancer patients and controls
10.3233/JAD-210191 16 BekrisL