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They produce the alpha-melanocyte stimulating hormone (alpha-MSH) that binds to the melanocortin 3 and 4 receptors (MC3Rs and MC4Rs) expressed by the second order neurons located in the periventricular nucleus and the lateral hypothalamic area (LHA) (51) (Figure 1)

Melanin c hai loi l eumelanin (to mu nu en, bo v da khi nng) v pheomelanin (to mu vng hng, gip da sng mn hn)

Avoid freezing the liquid solution, as freeze-thaw cycles can degrade the compound