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Clinical studies show that GLP-1 receptor sensitivity declines gradually over 12-24 months, and weight loss velocity naturally decreases as you approach a new metabolic set point

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Los participantes del ensayo clnico que tomaron tirzepatida, el medicamento vendido como Zepbound, perdieron 22,8 kilogramos (50 libras) en promedio durante 72 semanas, mientras que aquellos que tomaron semaglutida, o Wegovy, perdieron alrededor de 15 kilos (33 libras), de acuerdo con el estudio financiado por Lilly y que fue publicado en el New England Journal of Medicine

That set the stage for Wegovy, which was approved in June 2021 as the first high-dose semaglutide specifically for weight management

Keeping these timelines straight is key to getting the full benefit of your medication