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If the powder still has not dissolved after 30 minutes of periodic gentle swirling, the powder may have degraded from improper storage (exposure to heat, moisture, or extended room temperature storage)

The control group received physiological saline

These gastrointestinal effects are common and usually mild, but should be monitored if they persist or worsen.

10.1111/jre.12912 139 ZhangJ.LanT.HanX.XuY.LiaoL.XieL.et al (2021)