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Exercise and injection site selection Exercise increases blood flow to working muscles and surrounding tissue
DPP-4 inhibitors: Linagliptin: hepatobiliary excretion (no dose adjustment required in patients with renal impairment, making it preferred) Other DPP-4 inhibitors (sitagliptin, vildagliptin, saxagliptin, and alogliptin) are predominantly eliminated by the kidneys, so dosage must be adjusted in cases of severe renal dysfunction
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Screen participants for pancreatitis risk factors, and establish monitoring for symptoms (severe abdominal pain, elevated amylase/lipase) during the investigation period
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