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Every hour lost can blunt GLP-1-mediated appetite control
Mounjaro comes in a single-dose pen that you inject yourself once a week
With the GLP-1 receptor there is the pathway linked to insulin control, but also a pathway that recruits the signalling molecule beta arrestin, which causes the side effects but also results in the whole receptor and drug molecule being taken inside the cell, shutting down any further activity
[1] This sensation typically relates to the physiological changes that occur during significant weight loss rather than a direct pharmacological effect of the medication itself
Tirzepatide is a dual agonist at both GIP and GLP-1 receptors
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