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Description

A novel SHP-1/Grb2-dependent mechanism of negative regulation of cytokine-receptor signaling: contribution of SHP-1 C-terminal tyrosines in cytokine signaling

Cells were treated with the following inhibitors and metabolites: GSK864 (10M), KG (1mM), L-carnitine (1mM) and O-Acetyl-carnitine (1mM) for a period of 5 days, followed by inducing the DSBs with Tamoxifen (1M) and shield-1 (1M) for a period of 4 hours